An MCAS Guide to Springtime Joy
- Antonia Kenny

- Apr 25
- 4 min read
by Antonia at Unremarkable Me(lover of flowers, victim of their betrayal)
Ah, spring. The sun is shining, the birds are singing, and nature is bursting into vibrant life once again. It’s all very poetic—until your immune system mistakes a daffodil for a biological weapon.
Some people greet spring with bike rides and iced lattes. I greet it with three antihistamines, an endless supply of old-lady pocket tissues, and a facial expression that says, “Do I smell joy... or is that impending anaphylaxis?”
Welcome to the annual MCAS vs. Hay Fever showdown, featuring guest appearances by mysterious hives, weepy eyes, and at least one dramatic retreat from a bouquet of tulips.
This isn’t just hay fever. This is MCAS in bloom, baby. And if you're one of the blessed (biologically cursed) few juggling Mast Cell Activation Syndrome and seasonal allergies, then you know that spring isn't so much a season as it is a polite ambush.
So let’s talk about it—with laughter, with tissues, and with just enough sarcasm to get us through pollen season without crying. (Unless it's from sinus pressure. Which, let’s be real, it probably is.)
What Even Is Happening to Me?
One of the more delightful features of living with MCAS is never quite knowing what's trying to kill you. Is it the lilacs? The almond milk? A rogue gust of wind that passed through a freshly mowed lawn and now lives rent-free in your throat?
Hay fever, or seasonal allergic rhinitis if you're feeling fancy, is when your immune system overreacts to pollen. MCAS, on the other hand, is when your mast cells throw spontaneous raves in your body—and forget to clean up afterward.
Combine the two, and you’ve got a springtime game of allergic roulette. Except every chamber is loaded, and the gun is filled with... histamine.
If you're constantly asking yourself, “Is this a normal human response to nature, or is my body just being extra again?”—congrats, you're not alone. You're part of a beautiful, sneezy, slightly swollen club.
Learn more:
Mast Cell Action UK – Resources, community, and research advocacy.
The Mastocytosis Society – Detailed info on MCAS, diagnosis, and living well.
Survivable Spring Toolkit
(Because “gracefully enduring the season” is off the table)
Spring might be a sensory wonderland for most, but for those of us with overachieving mast cells, it's basically a live-action obstacle course. Over the years, I’ve developed a set of rituals, tools, and slightly panicked habits to survive the season without fully becoming a sneezy recluse.
The Antihistamine Arsenal No single antihistamine will do. I need options—like a fashionista with a closet full of black tops. I rotate between loratadine, cetirizine, and fexofenadine depending on which one is currently pretending to work.
Saline Nasal Spray = Liquid GoldI used to think nasal sprays were vaguely medieval. Now? I would drink the stuff if it were socially acceptable. It keeps my nose from turning into the Sahara and flushes out airborne horrors before they ruin my day.
Masks: Not Just for Pandemics AnymoreWearing a mask outside during peak pollen hours used to feel a bit dystopian. Now I see it for what it really is: personal air filtration, face-hiding convenience, and a sneaky way to avoid small talk with strangers.
The Windows Stay Shut Club Yes, it’s 20°C. Yes, the sun is shining. No, I will not be opening the windows. This home is a pollen-free fortress.
Showering After Going Outside Like I Just Got SlimedA tip from the allergy community: after you've been out in the botanical battlefield, change clothes and shower as soon as you’re back in. Bonus: you get to feel like the main character in a mildly tragic health documentary.
Tea, Honey, and a Touch of DenialHerbal teas are soothing. Local honey might help (though with MCAS, that’s a “consult your immune system first” situation).Denial? Surprisingly effective in small, non-clinical doses.
Tales from the Trenches
Let’s face it—there’s nothing quite like explaining to someone that no, you’re not contagious, your body’s just auditioning for a Shakespearean tragedy because you walked past a rosemary bush.
Here are some classic quotes from the histamine frontlines:
“I once broke out in hives from standing too close to a peach tree. I didn’t touch it. I didn’t even look at it funny.”
“Pollen counts were ‘low’ so I went for a walk. Five minutes in, my throat got tight, my ears itched inside, and I started crying. From joy? No. From birch trees.”
“I developed a reaction while watching a gardening show. I wasn’t even outside. That’s when I knew spring had gone too far.”
“My tip? Treat your immune system like an unstable relative. Don’t surprise it. Don’t feed it weird stuff. And for the love of all that is antihistaminic, don’t bring it flowers.”
MCAS in Spring: Drama or Just the Norm?
Mast Cell Activation Syndrome (MCAS) is all about mast cells going rogue. They release chemicals like histamine at wildly inappropriate times, causing reactions that range from annoying to apocalyptic.
Pollen? Fragrances? The emotional aura of a tree? Could be anything.
Combine that with hay fever, and your immune system becomes a histamine-powered drama queen. Every trigger is amplified. Every bucket is full. Every breeze feels personal.
The good news? You're not imagining it. Spring is a known MCAS trigger.The bad news? That doesn't make it easier.
For further help:
MCAS Hope – Advocacy and coping tips.
Ehlers-Danlos Support UK – MCAS Info – A reliable source for MCAS overlap with other chronic conditions.
Closing Thoughts (and a Tissue)
So here we are: another spring, another round of Guess That Allergen, another suspicious glance at the innocent-looking hydrangea. Living with MCAS during this season is like starring in your own nature documentary—except instead of majestic wildlife, it’s just you dodging pollen like you money.
But here’s the thing: you're not alone. You’re part of a secret society of springtime ninjas—ducking daffodils, side-eyeing picnic invites, and turning antihistamines into a dietary staple.
To my fellow mast-cell misfits: I see you. I salute you. I’ll be waving from inside my sealed, climate-controlled bubble—where I remain fabulously overprepared, slightly puffy, and deeply committed to surviving spring with flair.
And maybe—just maybe—I’ll even stop to smell the roses.(From a safe distance. While wearing a mask. With an EpiPen in my pocket. Obviously.)







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